Category: Therapeutics and Clinical Research

Prospective study: NRT use won’t prevent relapse

A prospective study published in the January 10, 2012 online edition of Tobacco Control found that patients using nicotine replacement therapy (NRT) were just as likely to relapse within 4 years as those who did not use a NRT. The study also found that heavily dependent smokers who used NRT without professional help were more [...]

Health Canada To Change Labeling of Varenicline

Based on data from a quit-smoking trial of 700 smokers with cardiovascular disease there was a slightly increased number of users in the trial that experienced “serious heart-related events”  Although the study is small and no conclusions have been released there is the possibility of an increased risk of heart attack or stroke in patients [...]

Many cancer patients continue to smoke after diagnosis

…despite a cancer diagnosis, 14 percent of the lung cancer patients and 9 percent of the colorectal patients were still lighting up…

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Fourth Annual Ottawa Conference: State of the Art Clinical Approaches to Smoking Cessation

Health Canada updates safety information for Champix

Although a slightly increased number of patients experienced serious heart-related events in the group treated with Champix compared to the group treated with placebo, the study was not adequately designed to be able to test the cardiovascular safety of Champix…

CMAJ: Pfizer advertises smoking cessation drug despite health warnings

Advertising for Pfizer’s Champix (vareniciline) has recently been rolled out which features patients claiming “I did it!”. However what these advertisements fail to announce is the potential cardiovascular risks associated with the use of varenicline. In a systematic review and meta analysis posted in the CMAJ in July, it was found that the use of [...]

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