..In a small, randomized study of 37 cocaine-dependent adults, those treated with Champix (varenicline) experienced significantly lower levels of reward effect from cocaine compared to those being treated with placebo..
A new study coming out of the Unites States is reporting that there is a substantial increased risk of reported depression/suicidal behaviour associated with varenicline (Champix) than with other smoking cessation products. The study looked at 3,249 reported cases of suicidal/self-injurious behaviour, 90% of which was associated with varenicine, 10% with bupropion, and 3% for [...]
An article in this morning’s Toronto Star by Tanya Talaga revealed that the Ontario government will begin to fund the smoking cessation drugs Zyban and Champix, as of August 4. This could cost between 10 and 15 million dollars a year, but is likely to result in great savings to the provincial health care system. [...]
Pfizer has put out a statement in response to the CMAJ varenicline article, asserting that the authors’ conclusions are misleading because they are based on a small number of cardiovascular events. Pfizer states that the study’s report of a 72% increase in adverse cardiovascular events among smokers using varenicline has been taken out of context. [...]
Dr. Andrew Pipe, Chief of the Division of Prevention and Rehabilitation at the University of Ottawa Heart Institute and Professor in the Faculty of Medicine at the University of Ottawa, was recently asked for his opinion on recent media attention surrounding Champix and FDA warning. Specifically, it was based on an analysis of a study, [...]
Canadian Family Physician | Vol 57: JUNE: Smoking Cessation and neuropsychiatric adverse effects. This article details the numerous psychiatric adverse effects patients can get when attempting smoking cessation and the importance of psychotherapy. Clinical practice guidelines recommend that every patient willing to quit should be offered counselling and pharamacotherapy, unless contraindicated. Reports of neuropsychiatric adverse [...]